Real-world evidence of dupilumab efficacy and risk of adverse events: a systematic review and meta-analysis
AS Halling, N Loft, JI Silverberg… - Journal of the American …, 2021 - Elsevier
Background Dupilumab, the first biological drug to be approved for the treatment of
moderate to severe atopic dermatitis in adolescents and adults, has shown good efficacy
and safety in clinical trials. Objective To evaluate real-world data on the efficacy and safety
of dupilumab in atopic dermatitis. Methods PubMed and EMBASE were searched for
observational studies with data on efficacy, drug survival, and safety of dupilumab for the
treatment of atopic dermatitis. Primary outcomes were mean percentage change in Eczema …
moderate to severe atopic dermatitis in adolescents and adults, has shown good efficacy
and safety in clinical trials. Objective To evaluate real-world data on the efficacy and safety
of dupilumab in atopic dermatitis. Methods PubMed and EMBASE were searched for
observational studies with data on efficacy, drug survival, and safety of dupilumab for the
treatment of atopic dermatitis. Primary outcomes were mean percentage change in Eczema …