Urine chemokines as biomarkers of human systemic lupus erythematosus activity
BH Rovin, H Song, DJ Birmingham… - Journal of the …, 2005 - journals.lww.com
The purpose of this study was to evaluate urine monocyte chemoattractant protein-1 (MCP-
1) and IL-8 as biomarkers of SLE flare. Urine was collected every 2 mo from patients who
were followed prospectively in the Ohio SLE Study. Renal and nonrenal flares were
identified and MCP-1 and IL-8 were measured by specific ELISA in samples that were
collected at flare. When available, MCP-1 and IL-8 were also measured in urine samples
before and after flare. For comparison, MCP-1 and IL-8 were measured in the urine of …
1) and IL-8 as biomarkers of SLE flare. Urine was collected every 2 mo from patients who
were followed prospectively in the Ohio SLE Study. Renal and nonrenal flares were
identified and MCP-1 and IL-8 were measured by specific ELISA in samples that were
collected at flare. When available, MCP-1 and IL-8 were also measured in urine samples
before and after flare. For comparison, MCP-1 and IL-8 were measured in the urine of …