The inflammatory microenvironment plays an important role in the pathogenesis and
progression of tumors and may be associated with somatic genomic alterations. We
examined the association of tumor-infiltrating T-cell density with clinical-pathologic
variables, tumor molecular subtype, and oncologic outcomes in surgically treated primary
prostate cancer occurring in patients of European-American or African-American ancestry.
We evaluated 312 primary prostate tumors, enriched for patients with African-American …