Molecular mechanisms of the PRL phosphatases
P Rios, X Li, M Köhn - The FEBS journal, 2013 - Wiley Online Library
P Rios, X Li, M Köhn
The FEBS journal, 2013•Wiley Online LibraryThe phosphatases of regenerating liver (PRLs) are an intriguing family of dual specificity
phosphatases due to their oncogenicity. The three members are small, single domain
enzymes. We provide an overview of the phosphatases of regenerating liver, compare them
to related phosphatases, and review recent reports about each phosphatase. Finally, we
discuss similarities and differences between the phosphatases of regenerating liver,
focusing on their molecular mechanisms and signalling pathways.
phosphatases due to their oncogenicity. The three members are small, single domain
enzymes. We provide an overview of the phosphatases of regenerating liver, compare them
to related phosphatases, and review recent reports about each phosphatase. Finally, we
discuss similarities and differences between the phosphatases of regenerating liver,
focusing on their molecular mechanisms and signalling pathways.
The phosphatases of regenerating liver (PRLs) are an intriguing family of dual specificity phosphatases due to their oncogenicity. The three members are small, single domain enzymes. We provide an overview of the phosphatases of regenerating liver, compare them to related phosphatases, and review recent reports about each phosphatase. Finally, we discuss similarities and differences between the phosphatases of regenerating liver, focusing on their molecular mechanisms and signalling pathways.
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