Reassessing the significance of intimal arteritis in kidney transplant biopsy specimens

IDR Salazar, MM López, J Chang… - Journal of the American …, 2015 - journals.lww.com
Intimal arteritis (the presence of v-lesions) in kidney transplant biopsy specimens is believed
to have major prognostic and diagnostic significance. We assessed the relationship of v-
lesions to prognosis in 703 indication biopsy specimens and used microarray-based
molecular tests to re-examine the relationship of v-lesions to rejection. v-Lesions were noted
in 49 specimens (7%) and were usually mild (v1). The presence of v-lesions had no effect on
graft survival compared with the absence of v-lesions. Pathologists using current …