[HTML][HTML] Identifying subphenotypes of antibody-mediated rejection in kidney transplants
The key lesions in antibody-mediated kidney transplant rejection (ABMR) are
microcirculation inflammation (peritubular capillaritis and/or glomerulitis lesions, abbreviated
“pg”) and glomerular double contours (cg lesions). We used these features to explore
subphenotypes in 164 indication biopsies with ABMR-related diagnoses: 137 ABMR (109
pure and 28 mixed with T cell–mediated rejection [TCMR]) and 27 transplant
glomerulopathy (TG), identified from prospective multicenter studies. The lesions indicated …
microcirculation inflammation (peritubular capillaritis and/or glomerulitis lesions, abbreviated
“pg”) and glomerular double contours (cg lesions). We used these features to explore
subphenotypes in 164 indication biopsies with ABMR-related diagnoses: 137 ABMR (109
pure and 28 mixed with T cell–mediated rejection [TCMR]) and 27 transplant
glomerulopathy (TG), identified from prospective multicenter studies. The lesions indicated …