Association of fluoroquinolones with the risk of aortic aneurysm or aortic dissection

C Gopalakrishnan, K Bykov, MA Fischer… - JAMA internal …, 2020 - jamanetwork.com
Importance Previous observational studies have suggested that fluoroquinolones are
associated with aortic aneurysm or dissection, but these studies may be subject to
confounding by indication or surveillance bias. Objective To assess the association of
fluoroquinolones with risk of aortic aneurysm or aortic dissection (AA/AD) while accounting
for potential confounding by fluoroquinolone indication and bias owing to differential
surveillance. Design, Setting, and Participants In an observational cohort study using a US …