[HTML][HTML] Early-life sugar consumption affects the rat microbiome independently of obesity

EE Noble, TM Hsu, RB Jones, AA Fodor, MI Goran… - The Journal of …, 2017 - Elsevier
Background The gut microbiome has been implicated in various metabolic and
neurocognitive disorders and is heavily influenced by dietary factors, but there is a paucity of
research on the effects of added sugars on the gut microbiome. Objective With the use of a
rodent model, our goal was to determine how added-sugar consumption during the juvenile
and adolescent phase of development affects the gut microbiome. Methods Forty-two
juvenile male Sprague-Dawley rats [postnatal day (PND) 26; 50–70 g] were given access to …