Clinical pharmacokinetics of doxycycline and minocycline
S Saivin, G Houin - Clinical pharmacokinetics, 1988 - Springer
S Saivin, G Houin
Clinical pharmacokinetics, 1988•SpringerDoxycycline and minocycline are second-generation tetracyclines. They are readily
absorbed, distributed throughout the organism as a function of their lipophilicity and
eliminated in both the urine and the faeces. The influence of age, renal disease, malnutrition
and hyperlipidaemia is reviewed, together with the main pharmacokinetic interactions.
absorbed, distributed throughout the organism as a function of their lipophilicity and
eliminated in both the urine and the faeces. The influence of age, renal disease, malnutrition
and hyperlipidaemia is reviewed, together with the main pharmacokinetic interactions.
Summary
Doxycycline and minocycline are second-generation tetracyclines. They are readily absorbed, distributed throughout the organism as a function of their lipophilicity and eliminated in both the urine and the faeces. The influence of age, renal disease, malnutrition and hyperlipidaemia is reviewed, together with the main pharmacokinetic interactions.
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