Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment―A consensus report from the Pulmonary Council of the ISHLT

GM Verleden, AR Glanville, ED Lease… - The Journal of Heart …, 2019 - jhltonline.org
The outcomes of transplantation vary widely by organ. Lung transplantation (LTx) has rather
poor long-term outcome, with a current median post-transplant survival of 6.0 years. 1, 2
Survival after organ transplantation is limited by both graft-related and non‒graft-related
factors. Allollograft failure remains the leading cause of morbidity and mortality across all
organ groups and is the major cause of death, accounting for> 40% of deaths beyond the
first year post-LTx. 1, 2 Our understanding of the patterns and pathophysiology of lung …