[HTML][HTML] Natural killer cells induce neutrophil extracellular trap formation in venous thrombosis
Essentials• Neutrophil extracellular traps (NETs) are generated during deep vein thrombosis
(DVT).• The role of interferon γ (IFNγ) and natural killer (NK) cells in NET formation was
studied.• IFNγ promote venous thrombosis through NET formation.• NK cell depletion
reduces DVT. Summary Background Neutrophils contribute to venous thrombosis through
the release of neutrophil extracellular traps (NETs), but the mechanism triggering their
formation remains unclear. In vitro data show that interferon (IFN)‐γ induces the formation of …
(DVT).• The role of interferon γ (IFNγ) and natural killer (NK) cells in NET formation was
studied.• IFNγ promote venous thrombosis through NET formation.• NK cell depletion
reduces DVT. Summary Background Neutrophils contribute to venous thrombosis through
the release of neutrophil extracellular traps (NETs), but the mechanism triggering their
formation remains unclear. In vitro data show that interferon (IFN)‐γ induces the formation of …