Prognostic role of NK cell percentages in bronchoalveolar lavage from patients with different fibrotic interstitial lung diseases
BAL cellularity and lymphocyte immunophenotyping offer insights into lung inflammatory
status. Natural killer (NK) cells are efficient effector cells, producing pro-inflammatory
cytokines. A better understanding of the biology of NK cells in BAL in the lungs is necessary
to improve the pathogenesis of fibrotic ILD and develop prospective targeted treatments. Our
aim was to analyse NK and NKT-like cell percentages in BAL from 159 patients with different
ILD: f-HP, f-NSIP, IPF and CTD-ILD, to evaluate their potential diagnostic/prognostic role …
status. Natural killer (NK) cells are efficient effector cells, producing pro-inflammatory
cytokines. A better understanding of the biology of NK cells in BAL in the lungs is necessary
to improve the pathogenesis of fibrotic ILD and develop prospective targeted treatments. Our
aim was to analyse NK and NKT-like cell percentages in BAL from 159 patients with different
ILD: f-HP, f-NSIP, IPF and CTD-ILD, to evaluate their potential diagnostic/prognostic role …
