Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation
Background There is significant heterogeneity within the primary graft dysfunction (PGD)
syndrome. We aimed to identify distinct grade 3 PGD phenotypes based on severity of lung
dysfunction and patterns of resolution. Methods Subjects from the Lung Transplant
Outcomes Group (LTOG) cohort study with grade 3 PGD within 72 h after transplantation
were included. Latent class analysis (LCA) was used to statistically identify classes based
on changes in PGD International Society for Heart & Lung Transplantation grade over time …
syndrome. We aimed to identify distinct grade 3 PGD phenotypes based on severity of lung
dysfunction and patterns of resolution. Methods Subjects from the Lung Transplant
Outcomes Group (LTOG) cohort study with grade 3 PGD within 72 h after transplantation
were included. Latent class analysis (LCA) was used to statistically identify classes based
on changes in PGD International Society for Heart & Lung Transplantation grade over time …