Hypertonic stress in the kidney: a necessary evil
MS Kwon, SW Lim, HM Kwon - Physiology, 2009 - journals.physiology.org
MS Kwon, SW Lim, HM Kwon
Physiology, 2009•journals.physiology.orgThe interstitium of the renal medulla is hypertonic, imposing deleterious effects on local
cells. At the same time, the hypertonicity provides osmotic gradient for water reabsorption
and is a local signal for tissue-specific gene expression and differentiation of the renal
medulla, which is a critical organ for water homeostasis.
cells. At the same time, the hypertonicity provides osmotic gradient for water reabsorption
and is a local signal for tissue-specific gene expression and differentiation of the renal
medulla, which is a critical organ for water homeostasis.
The interstitium of the renal medulla is hypertonic, imposing deleterious effects on local cells. At the same time, the hypertonicity provides osmotic gradient for water reabsorption and is a local signal for tissue-specific gene expression and differentiation of the renal medulla, which is a critical organ for water homeostasis.
American Physiological Society