[HTML][HTML] Relation between human vasopressin 1a gene variance, fat intake, and diabetes

S Enhörning, M Leosdottir, P Wallström… - The American journal of …, 2009 - Elsevier
Background Male arginine vasopressin 1a receptor knockout mice (V1aR−/−) display a
phenotype of low triglycerides and high glucose concentrations and high-fat-diet–induced
obesity and diabetes. Objective We investigated whether genetic variation of the human
arginine vasopressin 1A (AVPR1A) gene is associated with phenotypic features resembling
those of the V1aR−/− mouse. Design In a population-based cross-sectional study in
southern Sweden, middle-aged individuals (n= 6055) were examined in 1991–1994 …