Peripheral blood B cell depletion after rituximab and complete response in lupus nephritis
LMG Mendez, MD Cascino, J Garg… - Clinical Journal of the …, 2018 - journals.lww.com
Results A total of 53 (78%) participants achieved complete peripheral depletion (0 cells/µl)
in a median time of 182 days (interquartile range, 80–339). The median duration of complete
peripheral depletion was 71 days (interquartile range, 14–158). Twenty-five (47%)
participants with complete peripheral depletion achieved complete response, compared with
two (13%) without. Complete peripheral depletion was associated with complete response
(unadjusted odds ratio [OR], 5.8; 95% confidence interval [95% CI], 1.2 to 28; P= 0.03) …
in a median time of 182 days (interquartile range, 80–339). The median duration of complete
peripheral depletion was 71 days (interquartile range, 14–158). Twenty-five (47%)
participants with complete peripheral depletion achieved complete response, compared with
two (13%) without. Complete peripheral depletion was associated with complete response
(unadjusted odds ratio [OR], 5.8; 95% confidence interval [95% CI], 1.2 to 28; P= 0.03) …
