[HTML][HTML] The immune microenvironment of breast ductal carcinoma in situ
The host immune response has a key role in breast cancer progression and response to
therapy. However, relative to primary invasive breast cancers, the immune milieu of breast
ductal carcinoma in situ (DCIS) is less understood. Here, we profile tumor infiltrating
lymphocytes and expression of the immune checkpoint ligand programmed death ligand 1
(PD-L1) in 27 cases of DCIS with known estrogen receptor (ER), progesterone receptor, and
human epidermal growth factor 2 (HER-2) expression using tissue microarrays. Twenty-four …
therapy. However, relative to primary invasive breast cancers, the immune milieu of breast
ductal carcinoma in situ (DCIS) is less understood. Here, we profile tumor infiltrating
lymphocytes and expression of the immune checkpoint ligand programmed death ligand 1
(PD-L1) in 27 cases of DCIS with known estrogen receptor (ER), progesterone receptor, and
human epidermal growth factor 2 (HER-2) expression using tissue microarrays. Twenty-four …