Distinct macrophage populations throughout the body display highly heterogeneous
transcriptional and epigenetic programs. Recent research has highlighted that these profiles
enable the different macrophage populations to perform distinct functions as required in their
tissue of residence, in addition to the prototypical macrophage functions such as in innate
immunity. These 'extra'tissue-specific functions have been termed accessory functions. One
such putative accessory function is lipid metabolism, with macrophages in the lung and liver …