Antibodies raised against receptor-binding domain of Plasmodium knowlesi Duffy binding protein inhibit erythrocyte invasion

AP Singh, SK Puri, CE Chitnis - Molecular and biochemical parasitology, 2002 - Elsevier
Erythrocyte invasion by malaria parasites requires specific receptor-ligand interactions.
Plasmodium vivax and Plasmodium knowlesi are completely dependent on binding the
Duffy blood group antigen to invade human erythrocytes. P. knowlesi invades rhesus
erythrocytes by multiple pathways using the Duffy antigen as well as alternative receptors.
Plasmodium falciparum binds sialic acid residues on glycophorin A as well as other sialic
acid-independent receptors to invade human erythrocytes. Parasite proteins that mediate …