Sialic acids (Sias) are nine-carbon keto sugars primarily present on the terminal residue of
cell surface glycans. Sialic acid binding immunoglobulins (Ig)-like lectins (siglecs) are
generally expressed on various immune cells. They selectively recognize different linkage-
specific sialic acids and undertake a variety of cellular functions. Many pathogens either
synthesize or acquire sialic acids from the host. Sialylated pathogens generally use siglecs
to manipulate the host immune response. The present review mainly deals with the newly …