Analysis of microRNA expression profiling identifies miR-155 and miR-155* as potential diagnostic markers for active tuberculosis: a preliminary study
J Wu, C Lu, N Diao, S Zhang, S Wang, F Wang… - Human immunology, 2012 - Elsevier
To explore biologic behaviors and disease relevance of microRNAs (miRNAs) in the
development of active tuberculosis (ATB), we investigated the expression profile of
Mycobacterium tuberculosis (MTB) purified protein derivative (PPD)–induced miRNAs to
determine the specific miRNAs involved in the pathogenesis of ATB. The expression profile
of miRNA under PPD challenge was first measured using microarray analysis in peripheral
blood mononuclear cells isolated from ATB patients and healthy controls (HC). The …
development of active tuberculosis (ATB), we investigated the expression profile of
Mycobacterium tuberculosis (MTB) purified protein derivative (PPD)–induced miRNAs to
determine the specific miRNAs involved in the pathogenesis of ATB. The expression profile
of miRNA under PPD challenge was first measured using microarray analysis in peripheral
blood mononuclear cells isolated from ATB patients and healthy controls (HC). The …