Understanding latent tuberculosis: a moving target
PL Lin, JAL Flynn - The Journal of Immunology, 2010 - journals.aai.org
PL Lin, JAL Flynn
The Journal of Immunology, 2010•journals.aai.orgTuberculosis (TB) remains a threat to the health of people worldwide. Infection with
Mycobacterium tuberculosis can result in active TB or, more commonly, latent infection.
Latently infected persons, of which there are estimated to be~ 2 billion in the world,
represent an enormous reservoir of potential reactivation TB, which can spread to other
people. The immunology of TB is complex and multifaceted. Identifying the immune
mechanisms that lead to control of initial infection and prevent reactivation of latent infection …
Mycobacterium tuberculosis can result in active TB or, more commonly, latent infection.
Latently infected persons, of which there are estimated to be~ 2 billion in the world,
represent an enormous reservoir of potential reactivation TB, which can spread to other
people. The immunology of TB is complex and multifaceted. Identifying the immune
mechanisms that lead to control of initial infection and prevent reactivation of latent infection …
Abstract
Tuberculosis (TB) remains a threat to the health of people worldwide. Infection with Mycobacterium tuberculosis can result in active TB or, more commonly, latent infection. Latently infected persons, of which there are estimated to be~ 2 billion in the world, represent an enormous reservoir of potential reactivation TB, which can spread to other people. The immunology of TB is complex and multifaceted. Identifying the immune mechanisms that lead to control of initial infection and prevent reactivation of latent infection is crucial to combating this disease.
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