Mechanical loading leads to osteoarthritis-like changes in the hypofunctional temporomandibular joint in rats

Y Ikeda, I Yonemitsu, M Takei, S Shibata, T Ono - Archives of oral biology, 2014 - Elsevier
Objectives Temporomandibular joint (TMJ) hypofunction secondary to feeding a liquid diet in
the growing period leads to morphological hypoplasia. However, few studies have
evaluated the results of mechanical loading on the hypoplastic TMJ. This study investigated
whether TMJ hypofunction in rats causes osteoarthritis (OA)-like changes when exposed to
mechanical loading. Design Male 21-day-old Wistar rats were divided into four groups. The
first group (C) served as the control. In the second group (W), mechanical loading was …