Interleukin-37 as a biomarker of mortality risk in patients with sepsis
CX Wu, J Ma, H Yang, JB Zhang, CR Sun, Y Lei… - Journal of Infection, 2021 - Elsevier
Background Sepsis is a serious syndrome that is caused by an unbalanced inflammatory
response to infection and can cause high mortality. The role of interleukin-37 (IL-37) in
estimating the mortality in patients with sepsis remains unknown. This study aims to reveal
the clinical application of IL-37 as a potentially novel biomarker to predict mortality risk in
patients with sepsis. Methods The serum IL-37 level in 114 adult septic patient serum
samples on the day of intensive care unit (ICU) admission, 56 non-sepsis ICU patients, and …
response to infection and can cause high mortality. The role of interleukin-37 (IL-37) in
estimating the mortality in patients with sepsis remains unknown. This study aims to reveal
the clinical application of IL-37 as a potentially novel biomarker to predict mortality risk in
patients with sepsis. Methods The serum IL-37 level in 114 adult septic patient serum
samples on the day of intensive care unit (ICU) admission, 56 non-sepsis ICU patients, and …