Chimeric antigen receptor T-cell approaches to HIV cure
AS Kuhlmann, CW Peterson… - Current Opinion in HIV and …, 2018 - journals.lww.com
AS Kuhlmann, CW Peterson, HP Kiem
Current Opinion in HIV and AIDS, 2018•journals.lww.comDespite promising results in preclinical studies, only a handful of clinical trials have been
initiated worldwide. Several obstacles remain prior to successful application of HIV-specific
CAR T-cell therapies in patients. In this review, we survey the current state of the field, and
address paths towards realizing the goal of an efficacious HIV CAR T-cell product.
initiated worldwide. Several obstacles remain prior to successful application of HIV-specific
CAR T-cell therapies in patients. In this review, we survey the current state of the field, and
address paths towards realizing the goal of an efficacious HIV CAR T-cell product.
Summary
Despite promising results in preclinical studies, only a handful of clinical trials have been initiated worldwide. Several obstacles remain prior to successful application of HIV-specific CAR T-cell therapies in patients. In this review, we survey the current state of the field, and address paths towards realizing the goal of an efficacious HIV CAR T-cell product.
Lippincott Williams & Wilkins