Innate immunity and inflammation in systemic sclerosis
R Lafyatis, M York - Current opinion in rheumatology, 2009 - journals.lww.com
R Lafyatis, M York
Current opinion in rheumatology, 2009•journals.lww.comThese observations provide a new paradigm for understanding the relationship between
immunity/inflammation and fibrosis. New therapeutics, including TLR agonists and
antagonists, and IFN inhibitors are currently under investigation. Further understandings of
inflammasome-mediated fibrosis may provide further insights into SSc pathogenesis.
immunity/inflammation and fibrosis. New therapeutics, including TLR agonists and
antagonists, and IFN inhibitors are currently under investigation. Further understandings of
inflammasome-mediated fibrosis may provide further insights into SSc pathogenesis.
Summary
These observations provide a new paradigm for understanding the relationship between immunity/inflammation and fibrosis. New therapeutics, including TLR agonists and antagonists, and IFN inhibitors are currently under investigation. Further understandings of inflammasome-mediated fibrosis may provide further insights into SSc pathogenesis.
Lippincott Williams & Wilkins