[HTML][HTML] Food deprivation exacerbates mitochondrial oxidative stress in rat liver exposed to ischemia-reperfusion injury
M Domenicali, P Caraceni, M Dall'Agata… - The Journal of …, 2001 - Elsevier
Mitochondria undergo oxidative damage during reperfusion of ischemic liver. Although
nutritional status affects ischemia-reperfusion injury in the liver, its effect on mitochondrial
damage has not been evaluated. Thus, this study was designed to determine whether
starvation influences the oxidative balance in mitochondria isolated from livers exposed to
warm ischemia-reperfusion. Fed and 18-and 36-h food-deprived rats underwent partial
hepatic ischemia followed by reperfusion. Mitochondria were isolated before and after …
nutritional status affects ischemia-reperfusion injury in the liver, its effect on mitochondrial
damage has not been evaluated. Thus, this study was designed to determine whether
starvation influences the oxidative balance in mitochondria isolated from livers exposed to
warm ischemia-reperfusion. Fed and 18-and 36-h food-deprived rats underwent partial
hepatic ischemia followed by reperfusion. Mitochondria were isolated before and after …