Stress-activated cytokines and the heart: from adaptation to maladaptation
DL Mann - Annual review of physiology, 2003 - annualreviews.org
▪ Abstract The ability of the myocardium to successfully compensate for and adapt to
environmental stress ultimately determines whether the heart will decompensate and fail or
maintain preserved function. Despite the importance of the myocardial response to
environmental stress, very little is known with respect to the biochemical mechanisms that
are responsible for mediating and integrating the stress response in the heart. In the present
review we summarize recent experimental material suggesting that the cytokines expressed …
environmental stress ultimately determines whether the heart will decompensate and fail or
maintain preserved function. Despite the importance of the myocardial response to
environmental stress, very little is known with respect to the biochemical mechanisms that
are responsible for mediating and integrating the stress response in the heart. In the present
review we summarize recent experimental material suggesting that the cytokines expressed …
