Wound healing is one of the most complex processes in multicellular organisms, involving
numerous intra-and intercellular signalling pathways in various cell types. It involves
extensive communication between the cellular constituents of diverse skin compartments
and its extracellular matrix. Miscommunication during healing may have two distinct
damaging consequences: the development of a chronic wound or the formation of a
hypertrophic scar/keloid. Chronic wounds are defined as barrier defects that have not …