Dendritic cells and macrophages: sentinels in the kidney
CK Weisheit, DR Engel, C Kurts - Clinical Journal of the American …, 2015 - journals.lww.com
The mononuclear phagocytes (dendritic cells and macrophages) are closely related immune
cells with central roles in anti-infectious defense and maintenance of organ integrity. The
canonical function of dendritic cells is the activation of T cells, whereas macrophages
remove apoptotic cells and microbes by phagocytosis. In the kidney, these cell types form an
intricate system of mononuclear phagocytes that surveys against injury and infection and
contributes to organ homeostasis and tissue repair but may also promote progression of …
cells with central roles in anti-infectious defense and maintenance of organ integrity. The
canonical function of dendritic cells is the activation of T cells, whereas macrophages
remove apoptotic cells and microbes by phagocytosis. In the kidney, these cell types form an
intricate system of mononuclear phagocytes that surveys against injury and infection and
contributes to organ homeostasis and tissue repair but may also promote progression of …