[HTML][HTML] Spatially resolved transcriptomic analysis of acute kidney injury in a female murine model
Background Single-cell sequencing technologies have advanced our understanding of
kidney biology and disease, but the loss of spatial information in these datasets hinders our
interpretation of intercellular communication networks and regional gene expression
patterns. New spatial transcriptomic sequencing platforms make it possible to measure the
topography of gene expression at genome depth. Methods We optimized and validated a
female bilateral ischemia-reperfusion injury model. Using the 10× Genomics Visium Spatial …
kidney biology and disease, but the loss of spatial information in these datasets hinders our
interpretation of intercellular communication networks and regional gene expression
patterns. New spatial transcriptomic sequencing platforms make it possible to measure the
topography of gene expression at genome depth. Methods We optimized and validated a
female bilateral ischemia-reperfusion injury model. Using the 10× Genomics Visium Spatial …
