COVID-19–associated multisystem inflammatory syndrome in children (MIS-C): A novel disease that mimics toxic shock syndrome—the superantigen hypothesis

MN Rivas, RA Porritt, MH Cheng, I Bahar… - Journal of Allergy and …, 2021 - jacionline.org
As of mid-September, the novel severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has infected more than 30 million people, resulting in approximately 1 million deaths
worldwide, including more than 200,000 deaths in the United States alone. Fever, dry
cough, breathing difficulties, and gastrointestinal (GI) symptoms are typical features of
coronavirus disease-2019 (COVID-19). Although 80% of infected people develop a mild
disease, approximately 20% progress to severe COVID-19, which is associated with lung …