[PDF][PDF] The SARS-CoV-2 mRNA vaccine breakthrough infection phenotype includes significant symptoms, live virus shedding, and viral genetic diversity
Clin Infect Dis, 2021•scholar.archive.org
Little is known about SARS-CoV-2 'vaccine-breakthrough'infections (VBI). Here we
characterize 24 VBI in predominantly young healthy persons. While none required
hospitalization, a proportion endorsed severe symptoms and shed live virus as high as 4.13
x 103 PFU/mL. Infecting genotypes included both variant-of-concern (VOC) and non-VOC
strains.
characterize 24 VBI in predominantly young healthy persons. While none required
hospitalization, a proportion endorsed severe symptoms and shed live virus as high as 4.13
x 103 PFU/mL. Infecting genotypes included both variant-of-concern (VOC) and non-VOC
strains.
Abstract
Little is known about SARS-CoV-2 ‘vaccine-breakthrough’infections (VBI). Here we characterize 24 VBI in predominantly young healthy persons. While none required hospitalization, a proportion endorsed severe symptoms and shed live virus as high as 4.13 x 103 PFU/mL. Infecting genotypes included both variant-of-concern (VOC) and non-VOC strains.
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