General and abdominal obesity and incident asthma in adults: the HUNT study
B Brumpton, A Langhammer… - European …, 2013 - Eur Respiratory Soc
European Respiratory Journal, 2013•Eur Respiratory Soc
Measures of body mass index (BMI) and waist circumference define general obesity and
abdominal obesity respectively. While high BMI has been established as a risk factor for
asthma in adults, waist circumference has seldom been investigated. To determine the
association between BMI, waist circumference and incident asthma in adults, we conducted
a prospective study (n= 23,245) in a population living in Nord-Trøndelag, Norway in 1995–
2008. Baseline BMI and waist circumference were measured and categorised as general …
abdominal obesity respectively. While high BMI has been established as a risk factor for
asthma in adults, waist circumference has seldom been investigated. To determine the
association between BMI, waist circumference and incident asthma in adults, we conducted
a prospective study (n= 23,245) in a population living in Nord-Trøndelag, Norway in 1995–
2008. Baseline BMI and waist circumference were measured and categorised as general …
Measures of body mass index (BMI) and waist circumference define general obesity and abdominal obesity respectively. While high BMI has been established as a risk factor for asthma in adults, waist circumference has seldom been investigated.
To determine the association between BMI, waist circumference and incident asthma in adults, we conducted a prospective study (n=23,245) in a population living in Nord-Trøndelag, Norway in 1995–2008.
Baseline BMI and waist circumference were measured and categorised as general obesity (BMI ≥30.0 kg·m2) and abdominal obesity (waist circumference ≥88 cm in females and ≥102 cm in males). Incident asthma was self-reported new-onset cases during an 11-yr follow-up period. Odds ratios for asthma associated with obesity were calculated using multivariable logistic regression.
General obesity was a risk factor for asthma in females (OR 1.96, 95% CI 1.52–2.52) and males (OR 1.84, 95% CI 1.30–2.59). In females, after additional adjustment for BMI, abdominal obesity remained a risk factor for asthma development (OR 1.46, 95% CI 1.04–2.05). Abdominal obesity seems to increase the risk of incident asthma in females in addition to BMI, indicating that using both measures of BMI and waist circumference in females may be a superior clinical assessment for asthma risk than any measure alone.
European Respiratory Society