A third of nonfasting plasma cholesterol is in remnant lipoproteins: lipoprotein subclass profiling in 9293 individuals
Background and aims Increased concentrations of calculated remnant cholesterol in
triglyceride-rich lipoproteins are observationally and genetically, causally associated with
increased risk of ischemic heart disease; however, when measured directly, the fraction of
plasma cholesterol present in remnant particles is unclear. We tested the hypothesis that a
major fraction of plasma cholesterol is present in remnant lipoproteins in individuals in the
general population. Methods We examined 9293 individuals from the Copenhagen General …
triglyceride-rich lipoproteins are observationally and genetically, causally associated with
increased risk of ischemic heart disease; however, when measured directly, the fraction of
plasma cholesterol present in remnant particles is unclear. We tested the hypothesis that a
major fraction of plasma cholesterol is present in remnant lipoproteins in individuals in the
general population. Methods We examined 9293 individuals from the Copenhagen General …