Background A growing health problem, venous thromboembolism (VTE), including
pulmonary embolism (PE) and deep vein thrombosis (DVT), requires refined diagnostic and
therapeutic approaches. Neutrophils contribute to thrombus initiation and development in
experimental DVT. Recent animal studies recognized neutrophil extracellular traps (NETs)
as an important scaffold supporting thrombus stability. However, the hypothesis that human
venous thrombi involve NETs has not undergone rigorous testing. Objective To explore the …