Angiogenesis has traditionally been viewed from the perspective of how endothelial cells
(ECs) coordinate migration and proliferation in response to growth factor activation to form
new vessel branches. However, ECs must also coordinate their metabolism and adapt
metabolic fluxes to the rising energy and biomass demands of branching vessels. Recent
studies have highlighted the importance of such metabolic regulation in the endothelium
and uncovered core metabolic pathways and mechanisms of regulation that drive the …