Global gene expression changes of amniotic fluid cell free RNA according to fetal development

JH Jang, YW Jung, SH Shim, YJ Sin, KJ Lee… - European Journal of …, 2017 - Elsevier
Objective This study aimed to evaluate the effect of in utero fetal development on the cell-
free transcriptome of amniotic fluid by analyzing global gene expression in the amniotic fluid
supernatant obtained at different gestational ages from euploid fetuses Study design
Thirteen amniotic fluid samples were obtained from five individuals at 28 gestational weeks
and eight individuals at full term pregnancy. Transcriptome data previously analyzed by our
group from 14 euploid mid-trimester amniotic fluid samples were used for comparative …