Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth

R Parker, SR Dalziel - Cochrane database of systematic …, 2020 - cochranelibrary.com
R Parker, SR Dalziel
Cochrane database of systematic reviews, 2020cochranelibrary.com
Background Respiratory morbidity including respiratory distress syndrome (RDS) is a
serious complication of preterm birth and the primary cause of early neonatal mortality and
disability. Despite early evidence indicating a beneficial effect of antenatal corticosteroids on
fetal lung maturation and widespread recommendations to use this treatment in women at
risk of preterm delivery, some uncertainty remains about their effectiveness particularly with
regard to their use in lower‐resource settings, different gestational ages and high‐risk …
Background
Respiratory morbidity including respiratory distress syndrome (RDS) is a serious complication of preterm birth and the primary cause of early neonatal mortality and disability. Despite early evidence indicating a beneficial effect of antenatal corticosteroids on fetal lung maturation and widespread recommendations to use this treatment in women at risk of preterm delivery, some uncertainty remains about their effectiveness particularly with regard to their use in lower‐resource settings, different gestational ages and high‐risk obstetric groups such as women with hypertension or multiple pregnancies.
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