A condition with fibrosis of the bone marrow, extramedullary hemopoiesis, and splenic
enlargement was described one-half century ago. Its close relationship to chronic
granulocytic leukemia and polycythemia rubra vera or its classification as a separate entity
has stimulated much interest. In 1871 Wood 1 wrote of a" splenic variety of pseudoleukemia
or splenic cachexia" and speculated as to whether there was any consistent change in the
bone marrow. He described cases of splenomegaly associated with gelatinous …