[HTML][HTML] Barrett's esophagus and Barrett's-related dysplasia

JR Goldblum - Modern pathology, 2003 - Elsevier
Barrett's esophagus is a complication of chronic gastroesophageal reflux disease and can
be diagnosed when there is an endoscopic abnormality in which a biopsy shows evidence
of specialized columnar epithelium, characterized by the presence of acid mucin-containing
goblet cells. Much of the controversy in this body of literature relates to the complex anatomy
of the esophagogastric junction and the difficulty in precisely identifying this landmark at
endoscopy. By definition, in Barrett's esophagus, the squamocolumnar junction is proximal …