[HTML][HTML] Regulation of zinc metabolism and genomic outcomes

RJ Cousins, RK Blanchard, JB Moore, L Cui… - The Journal of …, 2003 - Elsevier
Differential mRNA display and cDNA array analysis have identified zinc-regulated genes in
small intestine, thymus and monocytes. The vast majority of the transcriptome is not
influenced by dietary zinc intake, high or low. Of the genes that are zinc regulated, most are
involved in signal transduction (particularly influencing the immune response), responses to
stress and redox, growth and energy utilization. Among the genes identified are uroguanylin
(UG), cholecystokinin, lymphocyte-specific protein tyrosine kinase (LCK), T-cell cytokine …