[HTML][HTML] A comparison of zinc metabolism, inflammation, and disease severity in critically ill infected and noninfected adults early after intensive care unit admission
BY Besecker, MC Exline, J Hollyfield, G Phillips… - The American journal of …, 2011 - Elsevier
Background: Zinc deficiency is a cause of immune dysfunction and infection. Previous
human studies have shown that the activation of the acute phase response alters zinc
metabolism. Whether the alteration in zinc metabolism is predictive of disease severity in the
setting of critical illness is unclear. Objective: We sought to determine whether differences
occur in zinc metabolism at the onset of critical illness between infected (septic) and
noninfected subjects. Design: We conducted this prospective study in an adult medical …
human studies have shown that the activation of the acute phase response alters zinc
metabolism. Whether the alteration in zinc metabolism is predictive of disease severity in the
setting of critical illness is unclear. Objective: We sought to determine whether differences
occur in zinc metabolism at the onset of critical illness between infected (septic) and
noninfected subjects. Design: We conducted this prospective study in an adult medical …