Activin A serum levels and aging of the pituitary-gonadal axis: a cross-sectional study in middle-aged and elderly healthy subjects

A Baccarelli, PS Morpurgo, A Corsi, I Vaghi… - Experimental …, 2001 - Elsevier
Aim of the study was to investigate activin A serum concentration in healthy adult males and
post-menopausal females over a wide age-range and its correlation to gonadotropins,
inhibin B and testosterone concentrations. The study included 73 males (aged 30–101
years) and 42 postmenopausal females (aged 50–104 years). Blood samples were
collected after an overnight fast to measure serum activin A, inhibin B, LH, FSH, and gonadal
steroid levels. A significant increase in serum activin A levels over age in both genders …