Isolation of retinal arterioles for ex vivo cell physiology studies
TM Curtis, D McLaughlin, M O'Hare, J Kur… - JoVE (Journal of …, 2018 - jove.com
The retina is a highly metabolically active tissue that requires a substantial blood supply.
The retinal circulation supports the inner retina, while the choroidal vessels supply the
photoreceptors. Alterations in retinal perfusion contribute to numerous sight-threatening
disorders, including diabetic retinopathy, glaucoma and retinal branch vein occlusions.
Understanding the molecular mechanisms involved in the control of blood flow through the
retina and how these are altered during ocular disease could lead to the identification of …
The retinal circulation supports the inner retina, while the choroidal vessels supply the
photoreceptors. Alterations in retinal perfusion contribute to numerous sight-threatening
disorders, including diabetic retinopathy, glaucoma and retinal branch vein occlusions.
Understanding the molecular mechanisms involved in the control of blood flow through the
retina and how these are altered during ocular disease could lead to the identification of …