[HTML][HTML] Intercellular adhesion molecule-1 (ICAM-1) regulates endothelial cell motility through a nitric oxide-dependent pathway

CG Kevil, AW Orr, W Langston, K Mickett… - Journal of Biological …, 2004 - ASBMB
Coordinated regulation of endothelial cell migration is an integral process during
angiogenesis. However, molecular mechanisms regulating endothelial cell migration remain
largely unknown. Increased expression of cell adhesion molecules has been implicated
during angiogenesis, yet the precise role of these molecules is unclear. Here, we examined
the hypothesis that intercellular adhesion molecule-1 (ICAM-1) is important for endothelial
cell migration. Total cell displacement and directional migration were significantly attenuated …