The predominant form of secreted colony stimulating factor-1 is a proteoglycan.
LK Price, HU Choi, L Rosenberg, ER Stanley - Journal of Biological …, 1992 - jbc.org
Colony stimulating factor-1 (CSF-1) is a homodimeric glycoprotein that humorally regulates
the proliferation and differentiation of mononuclear phagocytic cells and locally regulates
cells of the female reproductive tract. Alternative splicing of the human CSF-1 mRNA leads
to alternative expression of the CSF-1 homodimer as a secreted glycoprotein or as a
membrane-spanning molecule with cell surface biological activity. In the present study,
analysis of immunoaffinity-purified CSF-1 from mouse L929 cell medium by sodium dodecyl …
the proliferation and differentiation of mononuclear phagocytic cells and locally regulates
cells of the female reproductive tract. Alternative splicing of the human CSF-1 mRNA leads
to alternative expression of the CSF-1 homodimer as a secreted glycoprotein or as a
membrane-spanning molecule with cell surface biological activity. In the present study,
analysis of immunoaffinity-purified CSF-1 from mouse L929 cell medium by sodium dodecyl …
