Allergen-specific immunotherapy (SIT) is an etiology-based treatment for respiratory and
Hymenoptera-allergic diseases. Although introduced a century ago, SIT was not widely
accepted for many years until its efficacy in the treatment of both allergic rhinoconjunctivitis
and allergic asthma was demonstrated in appropriate double-blind, placebo-controlled trials
and its mechanism of action was better understood. The indications for allergen-specific
immunotherapy have been specified in consensus reports. Allergen-specific immunotherapy …