Characteristic neuropathology of leukomalacia in extremely low birth weight infants
K Deguchi, K Oguchi, S Takashima - Pediatric neurology, 1997 - Elsevier
Extremely low birth weight (ELBW) infants with periventricular leukomalacia (PVL) were
examined by neuropathological and immunohistochemical methods. Thirteen ELBW infants
of 85 infants with PVL, born at 23 to 27 weeks of gestation, showed a widespread type of
distribution of PVL from the deep to intermediate white matter. Immunohistochemistry
demonstrated glial fibrillary acidic protein (GFAP)-positive astrocytes to be increased in the
deep white matter, often spreading to the intermediate white matter, in all cases of PVL …
examined by neuropathological and immunohistochemical methods. Thirteen ELBW infants
of 85 infants with PVL, born at 23 to 27 weeks of gestation, showed a widespread type of
distribution of PVL from the deep to intermediate white matter. Immunohistochemistry
demonstrated glial fibrillary acidic protein (GFAP)-positive astrocytes to be increased in the
deep white matter, often spreading to the intermediate white matter, in all cases of PVL …