M2 macrophage infiltrates in the early stages of ANCA-associated pauci-immune necrotizing GN
Results Biopsies with pauci-immune necrotizing GN had a mean of 10 (range= 3–25)
normal-appearing glomeruli, a mean of 2 (range= 1–5) glomeruli with segmental fibrinoid
necrosis, and a mean of 2 (range= 1–11) glomeruli with cellular crescents. CD68+ and
CD163+ macrophages predominated at sites of fibrinoid necrosis in pauci-immune
necrotizing GN, exceeding the quantity of neutrophils and T cells (mean scores [SD]= 2.5
[0.7] and 2.2 [0.75] versus 0.6 [0.5] and 0.1 [0.3], respectively; P< 0.001). B and natural killer …
normal-appearing glomeruli, a mean of 2 (range= 1–5) glomeruli with segmental fibrinoid
necrosis, and a mean of 2 (range= 1–11) glomeruli with cellular crescents. CD68+ and
CD163+ macrophages predominated at sites of fibrinoid necrosis in pauci-immune
necrotizing GN, exceeding the quantity of neutrophils and T cells (mean scores [SD]= 2.5
[0.7] and 2.2 [0.75] versus 0.6 [0.5] and 0.1 [0.3], respectively; P< 0.001). B and natural killer …